Heart failure hospitalization and early re-hospitalization are among major challenges in the management of heart failure patients, along with high mortality and reduced quality of life. The vulnerable phase during the 30 days post-discharge is known to be a period of high risk for heart failure patients. This could be due to compromised cardiac function, particularly systolic function. Thus, it is of the utmost importance to improve systolic function rapidly, with a call to action from the hospital onwards. Several hospital-based strategies have been proven to reduce recurrent hospitalizations. The keys to success are patient education, optimization of treatment, and continuity of care.